The host Boston Red Sox are one victory away from reaching the World Series for the first time since 2007 and will have to defeat either Max Scherzer or Justin Verlander to get there.
Boston has a 3-2 lead over the Detroit Tigers in the American League Championship Series and Scherzer, the probable AL Cy Young Award winner, will attempt to even the series on Saturday.
Verlander would start Game 7 on Sunday if the Red Sox don't wrap up the series in six games.
Detroit third baseman Miguel Cabrera isn't displaying his MVP-caliber form due to groin and abdominal injuries and first baseman Prince Fielder has played 17 consecutive postseason games without an RBI.
"We have to go to Fenway and we have to fight hard to win a game," Cabrera said after the Tigers' 4-3 loss in Game 5 on Thursday. "If we do that, we have to keep fighting and get the next one."
Boston's Mike Napoli has been a force with a .375 average and two homers in the series, while designated hitter David Ortiz is 2-for-19 – with one of the hits being his memorable game-tying grand slam in Game 2 that saved the Red Sox from falling into an 0-2 hole.