Troy police say an early morning crash on I-75 near Big Beaver Road has left four people with life-threatening injuries.
Police said the driver of a silver Honda lost control just before 3 a.m.
The car rolled over and came to rest in the median.
The victims were taken to Royal Oak Beaumont.
Police are still investigating the accident but say alcohol isn't believed to be a factor.
Anyone who may have witnesses the crash is asked to call police at 248-524-3477.